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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b09e29f9afe55148b35f0ee1d5e91ff84f80bfe158f853500c1f60ef55ae2f02' 
  AND token = '4HtNAiPHjExaSnnQ+/gM0T6ZcVQ4uhjGPlwQ1JlU5Qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}