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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2ef629399686ed426049ccc7e0bd7c4e3dad649443180df4e1c863f10b7c6ab' 
  AND token = 'rZLgkZt/BE6tv0OTn1ZXT4KLrbd6qPWf1SUR5YrZKos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}