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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8739aa2df37120a4e80854f35d1ed20706a4ff0f472813c1a133a8399320b2bb' 
  AND token = 'T/gH1VlP4UDz6Aqm4wuqmDBrqw16AaH9oXqS7fcbVqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}