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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1453aac5a2719e2ffca282a07092cd6161ef02e3ad2bcbbeac857db9d2936a12' 
  AND token = 'vEeZ07IVr5a7VN+mprgY3kMFJZy10NMs3wystUNw3zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}