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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e42f2a1fa39f37ccbf7712a890620b896623ea291080b4aae3f44fa78ded54' 
  AND token = 'GMISPyX3mF+hwbJfpuyRSEzSS1EP+KoU4NhMhqblHlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}