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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59a110e3e5f92e0d1b145b4d0631959396fe7a5b19e8abfa5aad9811cabefe03' 
  AND token = '+k+66/Hpt3lu981E3wSB+S5n9tX1P1xUhWN6xO7iYcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}