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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22c381373f0377623510a9102ace7f72646abc09437f40ce277fc4b1fb738ac7' 
  AND token = 'UfGK2IYOsU4HVlxkVgRe4Sq/lN55++kiyC34C3EXP0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}