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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c722e24dc8b1dd874132a6ebc6679688c1cd8457dbf6a7de848906c1e3d6232f' 
  AND token = '3IxfHZ/KoTEgyCFtVs1zo7tDNwbdhzIAcNOa2ZjQIl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}