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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b32678e2a23f203e19cb55a935cf3c7a780f726da57b72b74be609981afe88a' 
  AND token = 'S7I0MIQ+ktiRMrGUHSxyjhsz3TMBZ7XS/E3muwHXLm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}