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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9427d65fa9ed5bcb9694983be2a73a2362c90e492cac1c9c450e121ec9856d36' 
  AND token = 'LcQSDgnSElg8hS+YgiJ04MfFMkkPSIaC/YOdcbd8/Gk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}