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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416c7c80053ca6e9d5f8d0e1424cd9c11768af67fde89abdf76c4a06f1d7710b' 
  AND token = 'lGV4z1NE3FWGQQWQyvVL2Vz+6QdqkzPrLJmOJzGJNNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}