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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '641252d85cb006fb91b4095e14442f9234de801032971a2e29d5a536e37e790f' 
  AND token = 'P74mIfyWLu+cmfsg6PPKZmvJjgBpsi16tLv9s7Z04oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}