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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67648a77269e14d42e4312a95d2a0b7a25d7dc19e63f450866c8a074a18c4824' 
  AND token = 'SaumZWMzLF/hvfzGy2lsvYQ4nOYDfooDTcNlLHUzpCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}