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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2216956a0be1c6fda20de490880f631247c5b8c17a80700e5b047c1a245ae00d' 
  AND token = 'ZJeDvNcCFKOpCyuv4gKXbnmwyqbhEuDwUySPhOu1Zp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}