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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28ee6f765266cc498ce3eb9851342e27e226fc20e1d82d785dd61de319802ef8' 
  AND token = 'XZY4ATiH3mBMHvt5HfPdJTGRQfyBrRSwOM/b/JI4R8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}