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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c15db16e750d44c5c5f1d50ed7c7f1809c15a021529da3ddaaf36491c6cbbff' 
  AND token = 'w9folUfP+zT3Pp/2ZuQQkfncKsxEc1gk07Q0Xlm+zjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}