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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b53fbdaef0f9d3e43ed87d3acc85255fc404e2d89d2008e8bdd5070646bc3c88' 
  AND token = 'WJ7rc3Iy00f4Qm/dPj1SxvoruPcXy0NU/6Y5vGDMezI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}