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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324e7ebe3ae285b657b727d91feb250d06f919647f5920ffa6e839bc6c4347b2' 
  AND token = 'EzzZRuZF9mF4BNuD7QNcMVm90nxqUSlC4rLP3WgqZFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}