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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ddcd5c2bd3389bef481a354c04e3daefcb3f450812d737a4f0b47a58173d926' 
  AND token = '38gpTMC0WiDjZ83rloj572SUMAIX27KhFSNd+cTN+UY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}