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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b28f52a225a76bdd2a76d4347c57738bf1035c7201a02a54b075938be13f7e64' 
  AND token = 'aHyo9h4BBRSEEz3u/TS0jgJqQMmvUesFr3F57nzP33E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}