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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '390d1095b26afc002cd290f98afd64c46e9d8241a94323b07edf6bf64c93f9da' 
  AND token = 'eE+h6FVJFtnyLpCaepjBRMe2TSqFSMsCM01hOSSFlaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}