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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7666b23d0fd7325892399a6539519c1104ccb0a9cc54a8fdfb4d2853e0e52a1' 
  AND token = '1a3HZDWbKH3DhzdSqNcPqL7N2Pa1YkNsoAJ7rHSmRu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}