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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4154aac18f80cfa908660d9b50c159b8ac59462edb227adde96f8ebfcbd80401' 
  AND token = 'OFmqYq1aZz6XC1i2myXeKL29ONV2r2ST/D6HLhMZx2Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}