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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e8f0d2a1781fa879dc7919024f1b08691190af1aee08f58a642fb18bfb45947' 
  AND token = 'TBdLQYD8v1m+gBoB6E9jYm+JBq3sH/eJmYOo1siFZcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}