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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643ac921a59ddecf005d9fa293002b1d1777d2dc4a93c42dcb4cd9d1feb4faba' 
  AND token = 'ZQeYaKftVQMuLs3YIzPiHZf3x7/vtlv5Vu4okrffQ68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}