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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe92235d38bd62fc70f05a57d49355bbd207a5775ca345a7e1448804666bedb' 
  AND token = 'IyPlwLG45qZz+0XG94R3JXfPhL2iCegLylKc6qDEaYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}