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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2af51d00e137aff16ea528967c7b79a8b5f36fba3f09b1a8a093c4815dac299' 
  AND token = 'De3WxJSLKqd5pM5e77U30PohD35kRzbzw7/Uq337His=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}