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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f535c73e0f642ee1bd968ac579382bab2b2a66c9f59b4ee1c0cbe185f5aff65' 
  AND token = 'tnKYVGxB6Nv8QO1PpFatd+eqe9/RRhPUtXH9LTr7dzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}