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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec715baa9ce09b5c2cee3d4ff67e94a22ce561e1aece1457db858e6934c3da3e' 
  AND token = 'BXILzT1Vma1jroXx/vYwxZjAr2Z/Hys8khOrRSCCI+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}