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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e6dfd644ea43bfb5e5c8f295b993716aa7c82ccbe3a065b9a7333ff0867412a' 
  AND token = 'ya4UAx64pWDRAbAR73wSS4IvESQcky0iwx0gR8sHM2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}