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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c82e46f2513e684c5b3812a2f80dc111a0aea543ed7df2d2687b1da264c0da6' 
  AND token = 'kt1sNQeY/Nvi+wPIhQFfj6i/FL8uqD+JaQosc00DVuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}