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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aaa4bfc1a6e64c9d92b4cf2c63bab002f225bdc814f3186d65f62280b5d735a4' 
  AND token = 'yIgNAWYgGAzRnTjJj0/2JGdPDyBJ9XoZ/abTVNTf3FQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}