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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '278ebcc6aa0f637842e8bd6a122f237b2e8830492438d05dc70607c009bbd202' 
  AND token = 'vDXlZAs2uzNk4GjW5mg4AFPMZ5s6a4vzeG5gNuMKJz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}