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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad43a168f2737949b71390ccd05fbb148314a7bcad05ed9c05e3b85b3808a62' 
  AND token = 'qaNgv1AAQfWYCfrY93ai5ru1x3OHZwDTMtSH3fj+bl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}