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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9ee280f307d1523c42e2a4156db2ca2c4da153fad727a2251bc9fda43f0df1c' 
  AND token = 'ixEGj973So9YrrrSbfoTO6PTMWXOWVLCH+2OSDPeLZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}