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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b649e7981549b65bcfa62920614142541ff3fe43043c2c1e33e844b8e5032d' 
  AND token = 'Pfc1XQ9imQXZpFGeU72tM4TWXqhhmT7LjiVkyUkQn+M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}