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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e9a555cb7421cc6abbe08674aea45ab66aaf4d5f3294756e29850f9dd52312' 
  AND token = 'ZKffZdGz358TzkoS/6S/Df+F6Q4HqnVFo2lakSYQwO0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}