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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2510160011ca281985f85d02a5076eac1e36e5bc61e499ab9483880d1dedfbf' 
  AND token = 'GXCkEA2HWdd1t7NKfEpwhLubT4IGzzxSuHL2Mqg8ozM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}