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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53eb722b8554c32c0a8000ed84bd6dca006e195672f504f1aa7f84740ed4cbe6' 
  AND token = 'bYogI9Gse4takkeBcQRmao6Oo/etuyY/3L965LJFEQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}