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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7280818777ed04e81a11aa9e5b7d5bfcdd9c41ee105e1701c2c87bb610647fe0' 
  AND token = 'nWz2jb5pJ9LLyRPZBGyMz1k+1BozDV/5CbOJ8JtvRrc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}