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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8defbc33f2dc3b56f55491c6f26caede4971322ffe89553414b38920a15d3855' 
  AND token = 'xSQt+6N5Q2PA+KBHXLnq1aDxkgXBe/XbO2MvurpXoac=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}