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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8e1e8968b1f8fb56714cea4a7a03a6a49258f1bdb05507f4d508fe2d8b0e43f' 
  AND token = 'aVwzlaE+xPQ82/C5UKcNdUKrS3QJVPFBar+2w2JsbKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}