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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5654c81fd2cba71bf4b63c53e455ec3be1314eaa4d6db0c50b991c8fc6603016' 
  AND token = 'E0KGQiZs9w9d5+mddyi0LjIzGt0oEKsr648suCbyGZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}