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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1fec7c25a9515dc7cd8cbd295c3a5e978d613331d23ab07fe3a083cb898e514' 
  AND token = '+oNhO3Xj2Q1RPqMfeoWPZxO9IWk5FMf4OHFzk+hxYyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}