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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4341290cbe30bde75078eb4f231d8cc6d4827a6b116ef51a30886814feb965d9' 
  AND token = '/K7rQ8hdt4BXiOjDrtUVeC99Mqnljqv63zDpBTe/tRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}