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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250f03ea483bd19fdefe891e6aa8fdb4cdd988d4df85eb107310e18260a4d5b6' 
  AND token = '49bWWl+/Wx0dSDzHVCDl7pRswE6zlwulq/xIDxb6Dw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}