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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256469323ef39180c142b3d223e384fb2c8f1d618a0cf61992b49f593c5c18c7' 
  AND token = 'YPAkd28ZCIS1ocp3lopL/ALIuD/iuiLY6DStGcocmSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}