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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755c1dad3d99b391cdb43bd95a61fb80509846c53f221a2c4314c23d4d057432' 
  AND token = 'CpVISYFmeZr46Ho1ob7GnOvrHNp7HgpIeK4t67iWXuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}