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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d987f54b245863353238b236007fbdf4f964b280b6680b5c7da3a61e40870fa' 
  AND token = 'F0yFzRlDRcE7PYMuUIwhjG0R2Qjq0y5Jn4tFU5BEn5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}