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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81da8b84f2b65da71b1da4359eb39a2b8043a49f6b04f8f79be9e13f13d2d454' 
  AND token = 'YxVT2QWQhwll90DQ7OsaPiVgY1XJVewHP5LQu4xz9oM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "table": {
      "message": "Impossible WHERE noticed after reading const tables"
    }
  }
}